Without animal research, polio would kill or cripple thousands of unvaccinated adults and children each year.
Animals in Research
Facts:
Even the most sophisticated technology cannot mimic the complicated interactions occurring among cells, tissues, and organs in a living body. Laboratory animals are essential in many areas of biomedical research because they have organs and body systems similar to humans and other animals and thus are often susceptible to the same diseases we are. The data derived from research on these animals can thus be applied to humans and other animals.
Care:
Quality research would be impossible if the animals involved in the study were not well cared for. In order to ensure the welfare of animals used in research, there are strict rules and guidelines for the care of each species of laboratory animal. Researchers are only allowed to conduct studies involving animals if they can prove that no alternative would produce accurate results, and must follow established guidelines for the care, housing, and enrichment of the animals in their care.
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Why use animals at all?
There are striking similarities between the physiological systems of humans and various species of animals. Much of what we know about the immune system has come from studies with mice. Research on dogs has provided a great deal of information about the cardiovascular system. more...
Importance
Even the most sophisticated technology cannot mimic the complicated interactions occurring among cells, tissues, and organs in a living body. Laboratory animals are essential in many areas of biomedical research because they have organs and body systems similar to humans and other animals and thus are often susceptible to the same diseases we are. The data derived from research on these animals can thus be applied to humans and other animals. 
Quality research would be impossible if the animals involved in the study were not well cared for. In order to ensure the welfare of animals used in research, there are strict rules and guidelines for the care of each species of laboratory animal. Researchers are only allowed to conduct studies involving animals if they can prove that no alternative would produce accurate results, and must follow established guidelines for the care, housing, and enrichment of the animals in their care. 
